Labels:text | screenshot | black and white | black | font | document OCR: ive to Later in life the patients become respon lot so GnRH administration, while they were n appears during their childhood; this phenomen onadal to be related to hypothalamic-pituitary- mature maturation as found in patients with pr Hers. puberty after treatment of virilising dis I agonists. Patients do not respond initially to GnR ocorticoid Recently, spironolactone, an antiminer bined and an antiandrogen agent, has been co omatase (a with testolactone, an inhibitor of P450 a ens to key enzyme in the conversion of andro oestrogens) as therapy for testotoxicosis erful Alternatively, cyproterone acetate, a po drogen antiandrogen that blocks the cytosolic a receptor, may be used on its own.
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